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* This investigation was aided by grants from the American Cancer Society and the Jane Coffin Childs Fund for Medical Research. 1 The following abbreviations are used: DMBA, dimethylbenz(a)anthracene; BA, benz(a) anthracene; 3'-Me-DAB, 3'-methyl-4-dimethylaminoazobenzene. 2 Huggins, C., L. C. Grand, and F. P. Brillantes, Nature, 189, 204 (1961). 3Huggins, C., S. Morii, and L. C. Grand, Ann. Surg., 154, Suppl. no. 6, 315 (1961). 4Huggins, C., and S. Morii, J. Exptl. Med., 114, 741 (1961). 6 Currie, A. R., J. E. Helfenstein, and S. Young, Lancet, II, 1199 (1962). 6 Dao, T. L., and Y. Tanaka, Proc. Soc. Exptl. Biol. Med., 113, 78 (1963). 7Dao, T. L., and Y. Tanaka, Cancer Res., 23, 1148 (1963). 8 Huggins, C., T. F. Deuel, and R. Fukunishi, Biochem. Z., 338, 106 (1963). 9 Huggins, C., and R. Fukunishi, J. Exptl. Med., in press. 10 We are indebted to Paul Schurr, the Upjohn Company, Kalamazoo, Michigan, for preparing a lipide emulsion of 7,12-DMBA. Prof. M. S. Newman, Ohio State University, Columbus, Ohio, generously provided 3,9-DMBA and 6,8-DMBA.

SPECIFIC COMPLEMENT-FIXING VIRAL ANTIGENS IN HAMSTER AND GUINEA PIG TUMORS INDUCED BY THE SCHMIDT-RUPPIN STRAIN OF AVIAN SARCOMA