Correction for Krieger et al., Mutations in thyroid hormone receptor α1 cause premature neurogenesis and progenitor cell depletion in human cortical development

MEDICAL SCIENCES Correction for “Mutations in thyroid hormone receptor α1 cause premature neurogenesis and progenitor cell depletion in human cortical development,” by Teresa G. Krieger, Carla M. Moran, Alberto Frangini, W. Edward Visser, Erik Schoenmakers, Francesco Muntoni, Chris A. Clark, David Gadian, Wui K. Chong, Adam Kuczynski, Mehul Dattani, Greta Lyons, Alexandra Efthymiadou, Faraneh Varga-Khadem, Benjamin D. Simons, Krishna Chatterjee, and Frederick J. Livesey, which was first published October 18, 2019; 10.1073/pnas.1908762116 (Proc. Natl. Acad. Sci. U.S.A. 116, 22754–22763). The authors note that “In Fig. 4D, the horizontal line that highlights the comparison between neuronal activity in the three control lines and one of the three THRA mutant lines was drawn to end above the TRα1-FS382 mutation, rather than the TRα1FS397 mutation. The placement of the horizontal line incorrectly indicated that neuronal activity in TRα1-FS382 mutation neurons was significantly lower than that of controls, whereas activity in TRα1-FS397 neurons was not. The figure has been amended, and now the horizontal line correctly indicates that neuronal activity in TRα1-FS397 neurons was significantly lower than that of controls, whereas activity in TRα1-FS382 neurons was not. We apologize for any confusion this labeling error may have caused.” The corrected Fig. 4 and its legend appear below. The authors also note that the author name Faraneh VargaKhadem should instead appear as Faraneh Vargha-Khadem. The corrected author line appears below. The online version has been corrected.