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In a previous communication to the PROCEEDINGS1 I reviewed the work of the past on polycythaemia, and reported a series of experiments carried out in the hope of determining if possible the process by which the number of erythrocytes per unit volume of blood is increased in acute experimental polycythaemia. Since then further experiments have been undertaken, some of which have already been reported.2 The results of these experiments, and others about to be published, are collected here in a brief summary of this work up to the present time. This complicated problem may be divided into four main parts: (1) The causes capable of producing an increase in number of erythrocytes per unit volume of blood. (2) Localization of these processes. (3) The manner in which the number of erythrocytes is increased. (4) The mechanism by which the red corpuscle content of the blood is controlled.

The Processes Taking Place in the Body by Which the Number of Erythrocytes Per Unit Volume of Blood is Increased in Acute Experimental Polycythaemia