Correction for Oyen et al., Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein
Author(s) -
David Oyen,
Jonathan L. Torres,
Ulrike Wille-Reece,
Christian F. Ockenhouse,
Daniel Emerling,
Jacob Glanville,
Wayne Volkmuth,
Yevel Flores-García,
Fidel Zavala,
Andrew B. Ward,
Charles R. King,
Ian A. Wilson
Publication year - 2018
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.1808460115
Subject(s) - circumsporozoite protein , plasmodium falciparum , biology , computational biology , antibody , virology , genetics , malaria , immunology
MICROBIOLOGY, BIOPHYSICS AND COMPUTATIONAL BIOLOGY Correction for “Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein,” by David Oyen, Jonathan L. Torres, Ulrike Wille-Reece, Christian F. Ockenhouse, Daniel Emerling, Jacob Glanville, Wayne Volkmuth, Yevel Flores-Garcia, Fidel Zavala, Andrew B. Ward, C. Richter King, and Ian A. Wilson, which was first published November 14, 2017; 10.1073/pnas.1715812114 (Proc Natl Acad Sci USA 114: E10438–E10445). The authors note that they inadvertently omitted references that reported on computational models of helical structures for the NANP repeats of circumsporozoite protein (CSP) (1–3), one of which is a recent publication that used a helical model of (NANP)6 to explain the multivalent CSP binding of an antiNANP antibody (3). The model described in Oyen et al., however, differs extensively from these previous models in that the NANP repeats adopt a wide, elongated spiral, compared for example to the tightly packed helix as described in ref. 3. The full references 1–3 appear below. The references should have been cited in an additional sentence, which should have appeared on page E10443, left column, first paragraph, to precede the sentence that begins on line 3 with “Many questions remain. . . .” The additional sentence should have appeared as follows: “Helical models have been predicted previously for the NANP repeats (1–3), but these differ substantially from the spiral conformation presented here.” The authors also note that Fig. S7 appeared incorrectly. The corrected Supporting figure and its legend appear below. The SI has been corrected online.
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