Open AccessNanoparticle decoration impacts airborne fungal pathobiology
Author(s) -
Dana Westmeier,
Djamschid Solouk-Saran,
Cecilia Vallet,
Svenja Siemer,
Dominic Docter,
Hermann Götz,
Linda Männ,
Anja Hasenberg,
Angelina Hahlbrock,
Kathrin Erler,
Christoph Reinhardt,
Oliver Schilling,
Sven Becker,
Matthias Gunzer,
Mike Hasenberg,
Shirley K. Knauer,
Roland H. Stauber
Publication year - 2018
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.1804542115
Subject(s) - indoor bioaerosol , nanoparticle , spore , human health , human pathogen , aspergillus fumigatus , biology , nanotechnology , microbiology and biotechnology , ecology , materials science , bacteria , medicine , environmental health , genetics
Significance In this work, we demonstrate that nanoparticles rapidly assemble on spores under physiologically and ecologically relevant conditions. We provide in vitro and in vivo evidence that nanoparticle coating of the clinically most relevant airborne fungal pathogen,Aspergillus fumigatus , can affect the pathobiological identity and fate of both fungal spores and nanoparticles. Our findings suggest that nanoparticle coating of bioaerosols may be relevant for ecology and human health.
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