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Hardwicke et al.’s article (1) challenges the concept that reactivating human memories, by way of retrieval, returns them to a labile form requiring reconsolidation. Several lessons emerge from their study. Although the authors replicate the majority of our original observations (2) (learning, offline consolidation), they observed no evidence for memory lability following retrieval. Three methodological differences suggest potential explanations for this partial failure to replicate.

Understanding the boundary conditions of memory reconsolidation