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Reply to Klitz and Niklasson: Can viral infections explain the cross-sectional Austrian diabetes data?
Author(s) -
Stefan Thurner,
Peter Klimek,
Michael Szell,
Georg Duftschmid,
Gottfried Endel,
Alexandra KautzkyWiller,
David C. Kasper
Publication year - 2013
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.1305494110
Subject(s) - cross sectional study , diabetes mellitus , virology , medicine , endocrinology , pathology
The vast majority of diabetes patients suffer from type II diabetes. There are several theories for potential causes of its development, the most favored being the "exhaustion" of beta-cells by chronic excess caloric intake combined with inactivity leading to obesity, diabetes, and cardiovascular disease. Viral infection could be a potential cause, however mainly for type I diabetes. Furthermore, autoimmunity might play a role in type I patients..

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