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With the passing of Dr. Elwood Jensen, the field of Molecular Endocrinology recently lost another of its major pioneers. Jensen is popularly credited with the discovery of the mammalian estrogen receptor, and the promulgation of this important molecule as a key player in female endocrine function and as a diagnostic tool and therapeutic target for breast cancer. His work led to treatments that extended and saved the lives of many women. Elwood V. Jensen was born in Fargo, North Dakota, in 1920. He was preschooled by his mother, a teacher, and entered grade school in Ohio, where he grew up and later matriculated at Wittenberg College. He received his doctorate in organic chemistry at the University of Chicago in 1944. Jensen entered the faculty as an Assistant Professor in the Ben May Laboratories at University of Chicago in 1947 and later did a sabbatical at the Swiss Federal Institute of Technology. While in Switzerland, he climbed the Swiss face of the Matterhorn—one of the highest peaks in the Alps—even though he had no mountaineering experience. In 1951, Jensen returned to the Ben May Laboratories for Cancer Research and became Director there in 1969 (Fig. 1). On a leave of absence in 1983 through 1988, he served as worldwide Research Director …

Elwood V. Jensen (1920–2012): Father of the nuclear receptors