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Juanes et al. (1) offer three specific arguments in response to our finding that “because even small to moderate-sized earthquakes threaten the seal integrity of CO2 repositories… large-scale [carbon capture and storage (CCS)] is a risky, and likely unsuccessful, strategy for significantly reducing greenhouse gas emissions” (2). We believe all three of their arguments are incorrect. First, Juanes et al. (1) contend that, because most earthquakes in the Earth’s crust occur at depths several kilometers greater than that proposed for CO2 repositories, their occurrence is not an indication of the likelihood of faulting in response to injection-related pressure increases. The opposite is true. In just the past 2 y, moderate-sized …

Reply to Juanes et al.: Evidence that earthquake triggering could render long-term carbon storage unsuccessful in many regions