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Hypophysectomy of the adult male rat depressed the activity of acid phosphatase and acid proteinase, but increased the activity of p-glucuronidase in the testis. Groups of rats were treated with FSH, LH or testosterone alone or in combination after 32 days of post-hypophysectomy regression (restoration experiment) for a further 32 days, or with FSH, testosterone or dihydrotestosterone alone or in combination commencing at 2 days after hypophysectomy (maintenance experiment) for a further 30 days.

australian journal of biological sciences

Studies on Testicular Function. II. Effects of FSH, LH, Testosterone and Dihydrotestosterone on Restoration and Maintenance of Lysosomal Enzyme Activity in the Testis of the Hypophysectomized Rat