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Male Wistar rats were hypophysectomized and the effects on spermatogenesis were quantified by stereological techniques. Restoration of normal spermatogenesis was attempted 32 days after hypo-physectomy by treatment with FSH (designated F), LH (L) or testosterone (T) singly or in combina-tion for a further 32 days. In another experiment, maintenance of spermatogenesis was attempted using FSH (F), testosterone (T) or dihydrotestoterone (D). Treatment began two days after hypo-physectomy and was continued for a further 32 days.

australian journal of biological sciences

Studies in Testicular Function. I. Quantitative Effects of FSH, LH, Testosterone and Dihydro-testosterone on Restoration and Maintenance of Spermatogenesis in the Hypophysectomized Rat