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Ribosomal RNA (rRNA), soluble RNA (sRNA), and DNA have been extracted from wool roots in good yield and purity. rRNA and sRNA were prepared by extracting wool roots with a hydrophilic salt and a phenol-cresol mixture and rRNA was selectively precipitated with m·cresol. DNA was extracted with a salt having lipophilic and chelating properties, together with the phenol-cresol mixture. Two·stage extraction procedures were essential for the preparation of stable, undegraded nucleic acids.

Keratin Biosynthesis II. Extraction and Characterization of Nucleic Acids from Wool Roots