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This study was designed to compare ischemic preconditioning with opening of mitochondrial adenosine triphosphate-sensitive potassium channels and Na(+)/H(+) exchange inhibition in an isolated heart model of cold storage, simulating the situation of cardiac allografts.

journal of thoracic and cardiovascular surgery

Ischemic preconditioning with opening of mitochondrial adenosine triphosphate–sensitive potassium channels or Na+/H+ exchange inhibition: Which is the best protective strategy for heart transplants?