English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The great challenge with biological membrane systems is the wide range ofscales involved, from nanometers and picoseconds for individual lipids, to themicrometers and beyond millisecond for cellular signalling processes. Whilesolvent-free coarse-grained membrane models are convenient for large-scalesimulations, and promising to provide insight into slow processes involvingmembranes, these models usually have unrealistic kinetics. One major obstacleis the lack of an equally convenient way of introducing hydrodynamic couplingwithout significantly increasing the computational cost of the model. Toaddress this, we introduce a framework based on anisotropic Langevin dynamics,for which major in-plane and out-of-plane hydrodynamic effects are modeled viafriction and diffusion tensors from analytical or semi-analytical solutions toStokes hydrodynamic equations. Using this framework, we obtain accuratedispersion relations for planar membrane patches, both free-standing and in thevicinity of a wall. We also briefly discuss how non-equilibrium dynamics isaffected by hydrodynamic interactions.

Hydrodynamic coupling for particle-based solvent-free membrane models