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NAFLD, liver component of the “metabolic” syndrome, has become the most common liver disease in western nations. Non‐invasive imaging techniques exist, but have limitations, especially in detection and quantification of mild to moderate fatty liver. In this pilot study, we produced attenuation curves from biomedical‐quality projection images of liver and fat using the MARS spectroscopic‐CT scanner. Difficulties obtaining attenuation spectra after reconstruction demonstrated that standard reconstruction programs do not preserve spectral information.

Pilot Study to Confirm that Fat and Liver can be Distinguished by Spectroscopic Tissue Response on a Medipix‐All‐Resolution System‐CT (MARS‐CT)