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A 74−year−old Japanese man newly pres− ented with gastric polyposis, 2 years after intermittent administration of lornoxi− cam 12 mg (a new potent nonsteroidal anti−inflammatory drug) and nizatidine 300 mg daily (a histamine2−receptor an− tagonist) for knee joint pain and abdomi− nal discomfort, respectively. Gastroscopy (Figure 1a, b) and double−contrast radio− graphy (Figure 1 c) showed multiple small hemispheric polyps circularly oriented in the gastric antrum, with tubular narrow− ing. On histology, the polyps were found to consist of inflamed granulation tissue, with immature regenerative epithelium (Figure 1d).

Gastric Inflammatory Polyposis after Long-Term Intermittent Use of Nonsteroidal Anti-Inflammatory Drugs and Histamine2-Receptor Antagonists

Gastric Inflammatory Polyposis after Long-Term Intermittent Use of Nonsteroidal Anti-Inflammatory Drugs and Histamine₂-Receptor Antagonists