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L-Proline (I) catalyzes the asymmetric aldol reaction between acetone and various aldehydes. In the case of hydroxy acetone, it gives anti-diols in excellent diastereoand enantioselectivities.1,2 L-Proline catalyzes the Michael reaction of ketones with nitro olefins to provide a variety of chiral Michael addition products. T hi s do cu m en t w as d ow nl oa de d fo r pe rs on al u se o nl y. U na ut ho riz ed d is tr ib ut io n is s tr ic tly p ro hi bi te d.

Pyrrolidine-2-carboxylic Acid(l-Proline)