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In an open clinical trial including 10 patients with psoriasis vulgaris the therapeutic efficacy of a combination of calcipotriol, dithranol and UVB phototherapy was compared to that of dithranol and UVB phototherapy alone. All patients received both regimens with right/left comparison of preselected lesions on corresponding extremities. The clinical evaluation was based on erythema, infiltration, scaling and plaque area by means of a modified PASI sum score. Evaluations were done once weekly for four weeks. The therapeutic efficacy of the combination of calcipotriol, dithranol and UVB phototherapy was significantly superior to that of dithranol and UVB alone at all time points.

Klinische Erfahrungen mit einer kombinierten Calcipotriol/Dithranol/UVB-Therapie im Vergleich zur Dithranol/UVB-Therapie bei Psoriasis vulgaris