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Endoscopic submucosal dissection (ESD) is now the reference method for en bloc resection of large colorectal neoplasia [1]. Nevertheless, appendix invasion is still considered a contraindication to resection because of the risk of perforation and the difficulty in finding the dissection space at the bottom of the appendix. We report on the case of a 72-yearold man referred for resection of a 4 cm granular laterally spreading tumor (LST) of the cecum (▶Fig. 1, ▶Video 1). The lesion had developed on the appendiceal orifice, invading it deeply. As previously demonstrated, we used a traction strategy with two clips and a rubber band [2]. After complete circumferential incision and trimming, we caught the lesion edge with the first clip, which was grasping a rubber band (▶Fig. 2). The second clip was then used to grasp the rubber band and stretch the lesion; the clip was then fixed to the opposite wall of the colon (▶Fig. 3). This traction method is flexible using stretching and relaxing of the rubber band to produce more or less traction, respectively. Greater stretching of the band resulted in strong traction, which allowed the mucosa of the appendix to be dissected and extracted through the appendiceal orifice (▶Fig. 4). Finally, we were able to cut the deep fibrotic fibers that fixed the mucosa at the bottom of the appendix. Pathological examination revealed a granular LST with high grade dysplasia, which was completely removed with free margins. There were no complications either during the procedure or in the postoperative period. The patient was monitored for 48 hours, given the known risk of early and late acute appendicitis of 3% and 5%, respectively [3]. In patients with an intact appendix, there is a high risk of incomplete resection for lesions that reach and enter the appendiceal orifice with invisible margins (Type 3) [4]. Video 1 Endoscopic submucosal dissection procedure with double clip and rubber band traction to allow complete R0 resection of a laterally spreading tumor invading the appendix. ▶ Fig. 1 Granular laterally spreading tumor with regular mucosal and vascular patterns. a White-light imaging; the appendiceal orifice is indicated by the blue arrow. b Far view with narrow-band imaging (NBI). c, d Close-up views with NBI. E-Videos

endoscopy

Traction strategy with clips and rubber band allows complete en bloc endoscopic submucosal dissection of laterally spreading tumors invading the appendix