English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

We obtained experience in 800 determinations of platelet survival time(PST) with a modified method according to Aster and Jandl . In 20 normal volunteers we obtained a mean T½ of 99 hours with a S.D. of 13.4 hours. The reproducibility of the method was obtained from two PST measurements with an interval of one week. The S.D. of replication was 13.4 percent. The reproducibility of PST over a long period of time (18-30 months) was determined from patients of the placebo group of a trialon patients with angina pectoris. Compared with the PST at entry in 72 patients the mean standard deviation in at least three determinations was 14.5%. Each single PST has a range of 90% reliability (T½ ± 2x S.D.) depending on the correlation factor between disappearance in comparison with time. Our mean correlation factor (R) is 0.92 with a range of 0.85-1.00). A single PST with a R of 0.92 has an S.D. of 15%, meaning that there is a significant difference between two PST determinations in a single individual when there is more than 30% difference. At entry 30% of angina patients has a shortened PST. After six months there was an increase of the PST in the Clofibrate treated group. After 18 months however there was also an increase in the placebo group. This means that no trial of drug effects on platelet survival can be accepted which are lacking a double blind setting and a control group.

The Clinical Interpretation of Platelet Survival with Cr51 Tagged Platelets