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Acute nonarteritic anterior ischemic optic neuropathy (NAION) is considered to be acute ischemia of the posterior ciliary arteries. Prostaglandin E1 (PGE1), a powerful microcirculation vasodilator, has been shown to improve ocular blood flow.

Nonarteritic anterior ischemic optic neuropathy treated with intravenous prostaglandin E1 and steroids