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A 5-month-old male infant suffered from massive upper gastrointestinal bleeding that resulted in a hemoglobin level of 48g/L when he was referred to our hospital. A 4.2-cm mass of mixed density was detected in the stomach by enhanced abdominal computed tomography (▶Fig. 1). No family history of polyposis was recorded and there were no dark spots on the lips, hands, or feet. Gastroscopy showed a rounded and smooth-contoured polyp-like mass in the posterior wall of the upper stomach (▶Fig. 2). Endoscopic submucosal dissection (ESD) was indicated because of the presence of the large polyp (▶Video 1). Abundant angiogenesis of the mass led to bleeding during the ESD procedure. Coagrasper hemostatic forceps were used for hemostasis. After the polyp had been resected from the stomach (▶Fig. 3), the mass was cut into small pieces with a hook knife and the pieces were taken out individually with a E-Videos

Successful endoscopic submucosal dissection of a large juvenile polyp in the stomach of an infant