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Background Staphylococcus aureus bacteraemia is frequently associated with complications and a high mortality. Recent retrospective studies provide evidence that infectious disease specialist consultations improve the outcome of patients with Staphylococcus aureus bacteraemia by increasing adherence to treatment standards. Methods In this retrospective, single-centre observational study, we investigated the impact of infectious disease consultations on the outcome of patients with Staphylococcus aureus bacteraemia at the Jena University Hospital applying logistic regression and survival analyses. The primary endpoint was intra-hospital mortality. Originalarbeit e179 Kimmig A et al. Infektiologische Konsile bei... Dtsch Med Wochenschr 2018; 143: e179–e187 Results We analysed patients (≥ 18 years) with Staphylococcus aureus bacteraemia between December 2012 and August 2015 (n = 297), of whom 159 received infectious disease consultations. Specialist consultations were associated with lower intra-hospital mortality (23 % without consultations, 11 % with consultations; multiple regression analysis: odds ratio = 0.27 [95 % confidence interval: 0.12 –0.64]; p = 0.003). Furthermore, the adherence to defined quality-of-care indicators differed. The complete implementation of all recommendations was associated with the lowest intra-hospital mortality rates. Conclusion Infectious disease consultations in patients with Staphylococcus aureus bacteraemia were associated with a lower intra-hospital mortality rate.

Infektiologische Konsile bei Patienten mit Staphylococcus-aureus-Bakteriämie – eine retrospektive Beobachtungsstudie am Universitätsklinikum Jena