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Recent developments in the software package OEDIPE - enabling the simulation of in vivo counting - to use the biokinetic data in the modelling of the internal contamination. As part of the improvement of calibration techniques of in vivo counting, the Labo- ratory of Internal Dose Assessment of IRSN has developed a computer tool, "OEDIPE", to model internal contamination, to simulate in vivo counting and to cal- culate internal dose. The previous version of this software enabled to easily model sources made of a single radionuclide and located in a single organ but could not repre- sent a mixture of radionuclides which distribution evolves from the time of intake according to the biokinetics of the radionuclides. The purpose of this article is to des- cribe a new facility developed in the software to allow the modelling of sources heterogeneous in composition and in distribution and optionally to automatically inte- grate the distribution of the activity in different tissues estimated by biokinetic calculation at any time since the intake. These new developments give the opportunity to study much more complex contamination cases and the influence of the biokinetics on the in vivo counting, leading to a better assessment of the calibration coefficients and of the corresponding uncertainties.

radioprotection

Développements apportés au logiciel OEDIPE de simulation de mesures anthroporadiamétriques pour la prise en compte des données biocinétiques dans la modélisation de la contamination interne