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In the forest onchocerciasis, almost all microfilariae are subepidermic (mean distance from the base of the epidermis : 115,04 µm ± 4,35).In the savanna onchocerciasis there is also a population inhabiting a slightly deeper site (mean distance from the base of the epidermis of the whole population : 138,67 µm ± 3,58). This deeper population may be responsible, to a large extent, for the ocular lesions.

Different localization of microfilariae ofO. volvulusin the savanna and in the forest ; potential clinical implications