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The paper establish and investigate an HIV-1 virus model with logistic growth, which also has intracellular delay and humoral immunity delay. The local stability of feasible equilibria are established by analyzing the characteristic equations. The globally stability of infection-free equilibrium and immunity-inactivated equilibrium are studied using the Lyapunov functional and LaSalles invariance principle. Besides, we prove that Hopf bifurcation will occur when the humoral immune delay pass through the critical value. And the stability of the positive equilibrium and Hopf bifurcations are investigated by using the normal form theory and the center manifold theorem. Finally, we confirm the theoretical results by numerical simulations.

Hopf bifurcation of an HIV-1 virus model with two delays and logistic growth