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m/s n° 6-7, vol. 33, juin-juillet 2017 DOI : 10.1051/medsci/20173306006 9. Wang J, Mauvoisin D, Martin E, et al. Nuclear proteomics uncovers diurnal regulatory landscapes in mouse liver. Cell Metab 2017 ; 25 : 102-17. 10. Matsuo T, Yamaguchi S, Mitsui S, et al. Control mechanism of the circadian clock for timing of cell division in vivo. Science 2003 ; 302 : 255-9. 11. Gentric G, Desdouets C. Polyploidization in liver tissue. Am J Pathol 2014 ; 184 : 322-31. essential factor for red blood cell function. Cell 2008 ; 134 : 353-64. 7. Mauvoisin D, Wang J, Jouffe C, et al. Circadian clockdependent and -independent rhythmic proteomes implement distinct diurnal functions in mouse liver. Proc Natl Acad Sci USA 2014 ; 111 : 167-72. 8. Neufeld-Cohen A, Robles MS, Aviram R, et al. Circadian control of oscillations in mitochondrial rate-limiting enzymes and nutrient utilization by PERIOD proteins. Proc Natl Acad Sci USA 2016 ; 113 : E1673-E82. RÉFÉRENCES

Des sondes fluorescentes hybrides pour l’imagerie « à la demande » des protéines cellulaires