English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

m/s n° 3, vol. 31, mars 2015 DOI : 10.1051/medsci/20153103010 3 Goemans NM, Tulinius M, van den Akker JT, et al. Systemic administration of PRO051 in Duchenne’s muscular dystrophy. N Engl J Med 2011 ; 364 : 1513-22. 4 Cirak S, Arechavala-Gomeza V, Guglieri M, et al. Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study. Lancet 2011 ; 378 : 595-605. 5 Goyenvalle A, Griffith G, Babbs A, et al. Functional correction in mouse models of muscular dystrophy using exon-skipping tricyclo-DNA oligomers. Nat Med 2015 ; 21 : 270-5. 6 Renneberg D, Bouliong E, Reber U, et al. Antisense properties of tricyclo-DNA. Nucleic Acids Res 2002 ; 30 : 2751-7. 7 Renneberg D, Leumann CJ. Watson-Crick base-pairing properties of tricyclo-DNA. J Am Chem Soc 2002 ; 124 : 5993-6002. 8 Kohler M, Clarenbach CF, Boni L, et al. Quality of life, physical disability, and respiratory impairment in Duchenne muscular dystrophy. Am J Respir Crit Care Med 2005 ; 172 : 1032-6. 9 Perronnet C, Vaillend C. Dystrophins, utrophins, and associated scaffolding complexes: role in mammalian brain and implications for therapeutic strategies. J Biomed Biotechnol 2010 ; 2010 : 849426. 10 Deconinck AE, Rafael JA, Skinner JA, et al. Utrophindystrophin-deficient mice as a model for Duchenne muscular dystrophy. Cell 1997 ; 90 : 717-27. gnement réglementaire appropriés, on peut craindre que certaines applications possibles et rationnelles soient abandonnées faute de débouchés économiques suffisants, générant de graves inégalités et désillusions au sein des populations de malades. ‡ Functional correction and cognitive improvement in dystrophic mice using splice-switching tricyclo-DNA oligomers

Transplantation d’hépatocytes humains dérivés de cellules souches dans le foie de souris