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Polarization sensitive optical coherence tomography (PS-OCT) has been used to visualize the orientation of the nerves in the retinal nerve fiber layer (RNFL) and to visualize the orientation of the collagen fibers in peripapillary sclera in retinas of healthy volunteers. Optic axis orientation images clearly visualize the nerve fibers leaving the optic nerve head (ONH) in all radial directions. Sclera orientation images show that the sclera consist of two layers, an inner layer with an orientation parallel to the RNFL orientation, and a deeper layer where the collagen is circularly oriented.

Polarization-sensitive optical coherence tomography as a tool to visualize the fiber direction of retinal nerves and peripapillary sclera