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In this work we present an approach for image processing accuracy increasing in fluorescence nanoscopy of single colloidal quantum dots with blinking fluorescent behavior. The approach is based on the estimation of parameters, describing the slow collective drift, according to the information about a long series of frames with fluorescent images of single blinking quantum dots. The results of collective drift compensation for single colloidal quantum dots CdSe / ZnS supper-resolution image are demonstrated.

Slow drift compensation in long-term measurements in fluorescence nanoscopy with blinking colloidal semiconductor quantum dots