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Growing concern about knowledge of aerosol transport in human lungs is caused by  great potential of use of inhaled pharmaceuticals. Second substantial motive for  the research is an effort to minimize adverse effects of particular matter  emitted by traffic and industry on human health.  We created model geometry of human lungs to 7th generation of branching. This  model geometry was used for fabrication of two physical models. The first one is  made from thin walled transparent silicone and it allows a measurement of  velocity and size of aerosol particles by Phase Doppler Anemometry (PDA). The  second one is fabricated by stereolithographic method and it is designed for  aerosol deposition measurements. We provided a series of measurements of aerosol  transport in the transparent model and we ascertained remarkable phenomena  linked with lung flow. The results are presented in brief. To gather how this  phenomena affects aerosol deposition in human lungs we used the second model and  we developed a technique for deposition fraction and deposition efficiency  assessment.  The results confirmed that non-symmetric and complicated shape of human airways  essentially affects transport and deposition of aerosol. The research will now  focus on deeper insight in aerosol deposition

Research of transport and deposition of aerosol in human airway replica