English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The objective of our study was to establish the possibility of safe and painless castration of males using only sedatives together with local anesthesia. Animals, before appropriate fixation, were intramuscularly injected with xylanit (active substance xylazine) at a minimum dose of 1 mg/kg of live weight and zoletil at a subanesthetic dose of 1 mg/kg of animal weight, the testes and scrotal skin were infiltrated with 2% lidocaine solution according to the generally accepted method in veterinary surgery. Before, during, and after surgery, nociception indicators were evaluated: blood pressure; heart rate and respiration rate; degree of pain relief depth (presence of pain and spontaneous movement). During the surgery, the heart rate decreased, on average, by 40-50 beats/minute from baseline values, the respiratory rate decreased, on average, by 10 breaths/minute, and there was a decrease in blood pressure. We found that pre-sedation of animals with xylanite and subanesthetic doses of zoletil followed by tissue infiltration with lidocaine allowed humanely performing orchidectomy, as well as minimizing the cost of general anesthesia and the duration of anesthesia aftereffect on the body.

Experimental and clinical justification of male orchidectomy under local anesthesia in combination with xylazine and subanesthetic doses of zoletil