English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

As a tumor suppressor protein, p53 is directly involved in the control of cell cycle arrest, which plays a crucial role in cell metabolism, growth, apoptosis and responses to different types of damage or stress processes. And since the tumor and cancer are usually related to the mutation or functional inactivation of the p53, it’s necessary to investigate the mechanism of p53 functioning the tumor and other disease, trying to figure out its drug design strategy. In this paper, a brief introduction of p53 is given, including the structure, function and properties. Subsequently, the relationship of p53 gene and cancer is also discussed. In the end, a new rational drug-design for disordered region of p53 was summarized

The development of p53 tumor diagnosis and drug design strategy in its disordered region