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The optimization and the characterization of a new amperometric biosensor based on acetylcholinestrase (AChE), immobilized on a graphite electrode modified with Pt-nanoparticles (PtNP), are reported. The G/PtNP-AChE biosensor was used for heavy metals detection. The degree of inhibition (%I), the kinetic constants of the inhibition process, as well as the influence of the PtNP presence on these parameters were estimated

Electrochemical Method for Heavy Metals Detection by Inhibition of Acetylcholinesterase Immobilized on Pt-nanoparticles Modified Graphite Electrode