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The analysis of diseases occurring is given in animals in the first 100 DIM. Determined milk content: MF, MP, pH, Ur, BHBA, Ac, calculated FPR. INCD in milk cows in the first 100 DIM is the second most widespread – 30.72 %. Among INCD, DSD and RSD predominate in the former – 38.8 % each, DMEO accounts for 20.4 % of disease cases. In 17.05 % of the examined animals, the FPR corresponded to optimal values, and in 82.95 % it was 1.10 or less, which may indicate the spread of subacute subclinical rumen acidosis in the animals of the studied population. Exceeding the upper limit of FPR, indicating the presence of ketosis in animals, has not been established. Studies revealed a double excess of Ur content in milk, and in animals with normal FPR values, the Ur content was 11.15 % (p &lt; 0.001) higher than in animals with reduced FPR. The pH of milk generally corresponded to the values of the physiological norm. The level of BHBA in milk was below the threshold values, but in the animal’s group with FPR 1.10 or less, the BHBA content in milk significantly (by 80.0 %, p &lt; 0.01) exceeded the BHBA content in animals with normal FPR values. Cows with a normal FPR value, the Ac level in milk was found to exceed the threshold value by 28.57 %, and in animals with low FPR values, the established excess was 141.43 % (p &lt;0.05).

Disease structure of milk cows and the effect of the mass fractions ratio of fat and protein in milk on the level of the metabolites