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We report in this paper a global and exhaustive overview of the various attempts reported in the literature to develop electrochemical microsensors for the direct determination of nitric oxide (NO) in biological systems. In this compilation, we address the physico-chemical characteristics and the performances (in term of sensitivity) of the numerous chemically modified microelectrodes that were specially designed for the determination of NO, without judging what the biological applications might be.

Design of electrochemical microsensors to monitor nitric oxide production in biological systems: a global compilation