English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Though this extensive use of electrochemical detection for applicative purposes, in no case in the current literature has the behaviour of an electrochemical detector been studied as a function of mobile phase parameters especially in partic ular ch ro m at ographic mechanisms such as ion pair ch romatography. The knowledge of such behaviour is important to optimise electrochemical detection after chromato graphic separation. Thus in this work several parameters related to analyte detection after HPLC separation, were investigated and the results obtained are r eported hereafter. In particular hy d roquinone was chosen as a re fe rence solute since its ch ro m at ographic retention and re d ox mechanism are we l l known. The paper consists of two sections. In the first one (detec tor characterisation) the behaviour and performance of the detector are described: the results obtained can be of prac tical use in order to esta blish the operative conditions also for the detection of other analytes. The second section (bulk and flow electrolysis) deals with the ef fect of flow rate on the ch ro m at ographic signal. The process occurring in the detector cell in the presence of an electroacti ve species is actually an electrolysis. Therefore, starting from the theory of bulk and fl ow electro ly s i s , a model for predicting the detector response as a function of eluent f l ow rate wa s applied and its agreement with ex p e rimental results wa s compared.

Theory of bulk and flow electrolysis and approach to parameter optimisation for chromatographic electrochemical detection