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Context. Direct observation of gamma-ray emission from the decay of $^{18}$Fejected in classical nova outbursts remains a major focus of the nuclearastrophysics community. However, modeling the abundance of ejected $^{18}$F,and thus the predicted detectability distance of a gamma-ray signal near 511keV emitted from these transient thermonuclear episodes, is hampered bysignificant uncertainties in our knowledge of the key $^{18}$F(p,$\alpha$)reaction rate. Aims. We analyze uncertainties in the most recent nuclearphysics experimental results employed to calculate the $^{18}$F(p,$\alpha$)reaction rate. Our goal is to determine which uncertainties have the mostprofound influence on the predicted abundance of $^{18}$F ejected from novae,in order to guide future experimental works. Methods. We calculated a widerange of $^{18}$F(p,$\alpha$) reaction rates using R-Matrix formalism, allowingus to take into account all interference effects. Using a selection of 16evenly-spaced rates over the full range, we performed 16 new hydrodynamic novasimulations. Results. We performed one of the most thorough theoretical studiesof the impact of the $^{18}$F(p,$\alpha$) reaction in classical novae to date.The $^{18}$F(p,$\alpha$) rate remains highly uncertain at nova temperatures,resulting in a factor ~10 uncertainty in the predicted abundance of $^{18}$Fejected from nova explosions. We also found that the abundance of $^{18}$F maybe strongly correlated with that of $^{19}$F. Conclusions. Despite numerousnuclear physics uncertainties affecting the $^{18}$F(p,$\alpha$) reaction rate,which are dominated by unknown interference signs between 1/2$^+$ and 3/2$^+$resonances, future experimental work should focus on firmly and preciselydetermining the directly measurable quantum properties of the subthresholdstates in the compound nucleus $^{19}$Ne near 6.13 and 6.29 MeV.

Uncertainties in the $^{18}$F(p,$\alpha$)$^{15}$O reaction rate in classical novae