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Decreased serum concentrations that substantially alter the growth of normal 3T3 cells alter neither the active and non-active components of unidirectional (86)Rb(+) influx nor the intracellular K(+) content when compared with cells in exponential growth. Thus the changes in K(+) transport (measured with (86)Rb(+) as an analogue for K(+) movements) that occur on density-dependent growth inhibition of the mouse 3T3 cell are not mimicked by serum deprivation of the cells before density inhibition.

biochemical journal

Effect of imposed serum deprivation on growth of the mouse 3T3 cell. Dissociation from changes in potassium ion transport as measured from [86Rb]rubidium ion uptake