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Single ribosomes account for 90% or more of the ribosome fraction of Xenopus laevis ovaries. These ribosomes have low endogenous activity in a cell-free protein-synthesizing system but synthesize polyphenylalanine in the presence of poly U under conditions comparable with those reported for mammalian or bacterial systems. These observations agree with the view that the ribosome is deficient in mRNA.

Ribosomes from Xenopus laevis ovaries and the polyuridylic acid-directed biosynthesis of polyphenylalanine