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Fiegelson & Conte (1954) could find no adaptive increase in galactose oxidation in adult rats fed on a galactose diet. Young rats grew better when fed on 30% of dry matter of the diet as lactose (Whittier, Cary & Ellis, 1935; Chowdhury & Sadhu, 1958), while high lactose or galactose feeding is toxic to rats (Ershoff & Deuel, 1944; Guha, 1931). These studies and those in galactosaemia (Handler, 1947; Schwarz, Goldberg, Konrower & Holzal, 1956) led us to study the rates of oxidation of galactose and glucose in erythrocytes and liver tissue in young rats fed on a lactose diet, since it was thought that the young animals were likely to show better adaptive formation of enzymes for galactose oxidation.

Rates of oxidation of galactose and glucose in erythrocytes and liver after lactose feeding