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1. The DPN+, DPNH, TPN+ and TPNH contents of a variety of animal tissues have been determined. 2. In all the tissues investigated DPN is present mainly in the oxidized form, whereas TPN is present chiefly and sometimes exclusively in the reduced form. 3. High total concentrations of both DPN and TPN are found in liver, adrenals, kidney and lactating mammary glands. The high level of TPN in ovary and the low levels in brain and voluntary muscle are also of interest.

A preliminary investigation of the hormonal control of the hexose monophosphate oxidative pathway