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theory. Further, trypsin and other proteolytic enzymes, by destroying the protein part of thromboplastin, would increase its dissociation and speed the transfer of cephalin to prothrombin, thus providing a mechanism for the action of trypsin on the compound, the practical significance of which Ferguson has stressed. In the case of those clotting factors which are enzymes, the theory becomes the well-known theory of Michaelis and Menten. From the foregoing it is evident (1) that this reaction of heparin should be considered in experiments requiring its use, and (2) that in studies on blood clotting, heparin activity may be affected by the presence of factors not usually considered.

The isolation of behenic acid from refined mona wax