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THE factors responsible for the pathological condition leading to failure of normal growth in rats kept on a vitamin A-deficient diet are not exactly known. Since the appetite of such rats is less than that of normal rats, the most obvious explanation of the decreased rate of growth would be an insufficient food intake. A second possible cause of the disturbance of rate of growth might be a decreased absorption of food from the alimentary canal. This latter is suggested by the fact that frequently gastro-intestinal disturbances are associated with this dietetic defect. In this paper a preliminary investigation of these two suggestions is described.

The absorption of nitrogen and of fat from the alimentary canal of rats kept on a vitamin A-deficient diet