English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Stereolithographic 3D-printing (SLA) permits facile fabrication ofhigh-precision microfluidic and lab-on-a-chip devices. SLA photopolymers oftenyield parts with low mechanical compliancy in sharp contrast to elastomers suchas poly(dimethyl siloxane) (PDMS). On the other hand, SLA-printable elastomerswith soft mechanical properties do not fulfill the distinct requirements for ahighly manufacturable resin in microfluidics (e.g., high-resolutionprintability, transparency, low-viscosity). These limitations restrict ourability to print microfluidic actuators containing dynamic, movable elements.Here we introduce low-viscous photopolymers based on a tunable blend ofpoly(ethylene glycol) diacrylate (PEGDA, Mw~258) and poly(ethylene glycolmethyl ether) methacrylate (PEGMEMA, Mw~300) monomers. In these blends, whichwe term PEGDA-co-PEGMEMA, tuning the PEGMEMA-to-PEGDA ratio alters the elasticmodulus of the printed plastics by ~400-fold, reaching that of PDMS. Throughthe addition of PEGMEMA, moreover, PEGDA-co-PEGMEMA retains desirableproperties of highly manufacturable PEGDA such as low viscosity, solventcompatibility, cytocompatibility and low drug absorptivity. WithPEGDA-co-PEGMEMA, we SLA-printed drastically enhanced fluidic actuatorsincluding microvalves, micropumps, and microregulators with a hybrid structurecontaining a flexible PEGDA-co-PEGMEMA membrane within a rigid PEGDA housing.These components were built using a custom "Print-Pause-Print" protocol,referred to as "3P-printing", that allows for fabricating high-resolutionmultimaterial parts with a desktop SLA printer without the need forpost-assembly. SLA-printing of multimaterial microfluidic actuators addressesthe unmet need of high-performance on-chip controls in 3D-printed microfluidicand lab-on-a-chip devices.

Tunable Resins with PDMS-like Elastic Modulus for Stereolithographic 3D-printing of Multimaterial Microfluidic Actuators