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In an attempt to find novel anti-mycobacterial agents, novel acetylene containing 2-(2-hydrazinyl)thiazole derivatives have been synthesized and evaluated against  Mycobacterium tuberculosis .

rsc advances

Acetylene containing 2-(2-hydrazinyl)thiazole derivatives: design, synthesis, andin vitroandin silicoevaluation of antimycobacterial activity againstMycobacterium tuberculosis