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Dissociation energies  D  e  for B⋯A = B +A can be written  D  e  =  c ′ N  B  E  A , where  N  B  and  E  A  are the nucleophilicities and electrophilicities of the Lewis base B and the Lewis acid A, respectively.

A reduced electrophilicity for simple Lewis acids A involved in non-covalent interactions with Lewis bases B