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Homodimerization of a proline-rich antimicrobial peptide  via  bioconjugation to perfluoroaromatic linkers confers increased antimicrobial, antibiofilm and immunomodulatory activity. The dimers are promising new therapeutic leads against WHO priority multidrug resistant bacteria.

Enhancing proline-rich antimicrobial peptide action by homodimerization: influence of bifunctional linker