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ZIF-8 is regarded as a carrier to capture HPBI and eventually the adsorption of the pore structure would saturate, with altering the luminescent intensity. ZIF-8 may be used to sensitively detect nanoscale molecules  via  changes in fluorescence.

Tuning luminescence of the fluorescent molecule 2-(2-hydroxyphenyl)-1H-benzimidazole via zeolitic imidazolate framework-8