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The He bubble will initially nucleate around V Be2 . Then the nucleation of the He bubble will occur around the divacancy of V Be2 V Be1  and the trivacancy of V Be2 V Be1 V Be3 . The presence of H atoms will significantly influence the nucleation of the He bubble.

Aggregation of retained helium and hydrogen in titanium beryllide Be12Ti: a first-principles study

Aggregation of retained helium and hydrogen in titanium beryllide Be₁₂Ti: a first-principles study